Lepromatous leprosy with leprotic reaction II type erythema nodosum complicated with peripheral arterial disease
##plugins.themes.bootstrap3.article.main##
The leprosy is as old as humanity; nevertheless, a number of aspects related to several factors like etiologic agent, epidemiology, immunology, histopathological changes and treatment are still investigated. These factors developed within its evolutionary context. The ccurrent trend indicates a worldwide decrease in incidence and prevalence of this disease; however, the reaction episodes occurring in the course of the disease take place in a high percentage. The causes of these complications are not fully understood yet, but hard work is being done in search of the intimacies of leprotic reactions. These statuses are presented in the whole spectrum of the illness and the erythema nodosum is an important and frequent complication in the multibacillary patients.This complication characteristic of leprosy, it is added to this case another condition known as peripheral arterial disease which severely complicated the lepromatous leprosy and leprotic reaction, resulting in tissue necrosis of lower limbs by critical ischemia. In this case, there were diagnostic difficulties because of the bizarre clinical manifestation presented at the onset of complications. However, after 1-year follow-up it was concluded that the patient was in two different entities.
Downloads
##plugins.themes.bootstrap3.article.details##
Rodríguez G, Orozco L. C. Lepra. Instituto Nacional de Salud, 1996.
Rivas A, Gómez L. Lepra.Rev Asoc Col Dermatol 2008 sep;16(3):196-207.
Rodríguez G, Pinto R. La lepra. Imágenes y conceptos. 1a Edición. Editorial Universidad de Antioquia 2007.
Poletti E, García C, Márquez F. Fenómeno de 8. Lucio en paciente con lepra Lepromatosa Dermatología 2009 ene-mar;7(1):1-10.
Walker S, Lockwood D. Leprosy type 1, (reversal) 9. reactive and their management. Lepr rev 2008;79:372-386.
Mastrangelo G, Da Silva N, Scoizzato L. Leprosy 10. Reaction: the effect of gender and household contacts. Men Inst Oswaldo Cruz 2011 feb;106(1):92-96.
Serrano F, Conejero H, Conejero A. Enfermedad Arterial Periférica. Aspectos fisiopatológicos, clínicos y terapéuticos. Rev Esp Cardiol 2007;60(9):969-982.
Bennett P, Silverman S. and Gill P. Hypertension and peripheral arterial disease. Journal of Human Hypertension 2009;23:213-216.
Olin J. Masterclass series in peripheral arterial disease. Hypertension and peripheral arterial disease. Vascular Medicine 2005;10:241-246.
Clement D, De Buyzere M, and Duprez D. Hypertension in peripheral arterial disease. Current Pharmaceutical Design 2004;10:3615-3620.