Reproducibility of clinical measurements
Keywords:Validity, reliability, reproducibility, agreement, concordance
In the clinical setting as in research there is great interest in ensuring the quality of measurings as a basis for decision making. The quality of a measurement depends of two properties: The validity and reliability. While the validity expresses the degree of the measurement of the phenomenon of interest, the accuracy of a measurement is evaluated calculating the reproducibility of multiple measurements. This paper discusses the concepts of validity and reliability of a measurement and its clinical and epidemiological interpretation. Additionally discusses concepts of statistical agreement, concordance and correlation and presents a brief summary of the available methods for assessing the reproducibility both numerical and graphical.
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