Update on Guillain-Barre Syndrome

Síndrome Guillain-Barré: Un mirada actual


Guillermo González Manrique
Germán Giraldo Bahamon
Alejandro González Motta
Cristhian Felipe Ramirez Ramos

Guillain-Barré Syndrome is the most common cause of acute, non-traumatic flaccid paralysis in the world. It is a neurological emergency, causing a rapidly progressive polyneuropathy of sudden onset, generally with lower limb and lumbar pain, muscle weakness and paresthesias, progressing into an ascending symmetric paralysis with areflexia. Life-threatening consequences can occur if the respiratory muscles, cranial nerves or components of the autonomic system are compromised. Clinical presentation encompasses seven different subtypes associated with the immune agents involved in its pathophysiology. Diagnosis is based on clinical presentation, with electrophysiological findings comfirming a demyelinating pattern, F wave, and H reflex abnormalities. Cerebrospinal Fluid characteristic findings include albumino-cytological dissociation: an elevated protein level without an increase in cell count.



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Author Biographies / See

Guillermo González Manrique, Hospital Universitario Hernando Moncaleano Perdomo de Neiva.

Neurólogo clínico, Universidad Nacional de Colombia. MD. Internista, Universidad Surcolombiana. Jefe del Departamento
de Neurofisiología Hospital Universitario Hernando Moncaleano Perdomo de Neiva. Docente de medicina interna pregrado,
Universidad Surcolombiana. Docente de postgrado de medicina interna – Área neurología, Universidad Surcolombiana.

Germán Giraldo Bahamon, Hospital universitario Hernando Moncaleano Perdomo de Neiva

MD. Internista universidad Surcolombiana. Hospital universitario Hernando Moncaleano Perdomo y Clínica Medilaser.
Neiva Huila.

Alejandro González Motta, Instituto Nacional de Cancerología ESE. Bogotá D.C.

MD. Pontificia Universidad Javeriana. Residente de Oncología Radioterapia. Instituto Nacional de Cancerología ESE.
Bogotá D.C.

Cristhian Felipe Ramirez Ramos, Hospital universitario Hernando Moncaleano Perdomo de Neiva

Residente de Medicina Interna, Universidad Surcolombiana. Hospital Universitario Hernando Moncaleano Perdomo.
Neiva Huila.


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