Progressive disseminated histoplasmosis in a HIV-free patient
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Objective. To report a case of progressive disseminated histoplasmosis in a patient without immunodeficiency, HIV Elisa negative and discussion regarding the clinical presentation and diagnosis. Study design: Clinical case report and literature review. Methods. Medical history, histopathology, paraclinics' report, review of articles published in indexed journals. Results. The patient has 1-month length symptoms: weight loss, hemoptysis, progressive dysphagia, skin lesions and ulcerated mucosa. In biopsies taken, intracellular blastoconidias and yeast were identified in lymph tissues, gastric mucosa and bone marrow. Conclusions: It is a case of progressive histoplamasmosis in HIV-free patients with lung, gastric and lymphatic tissue involvement.
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