Perinatal commitment of pregnant with tuberculosis, Hospital Universitario "Dr. José Eleuterio González", en Monterrey, Nuevo León, México 2004-2012

Abstract

The aim of the present study was to investigate the maternal and perinatal outcomes of pregnancies associated with tuberculosis and compared with pregnant women unaffected by tuberculosis. Materials and methods. A retrospective, observational, comparative and prevalence study took place at the Hospital Universitario "Dr. José Eleuterio González", in Monterrey, Nuevo León, Mexico. A review of clinical history of pregnant women with tuberculosis in a 8-year period, from December 2004 to October 2012 was made. Both maternal and perinatal results were compared with those of pregnant women unaffected by tuberculosis, undergoing the same parity and of the same age. Results. The prevalence of pregnant women with tuberculosis was 0.26%. A statistically significant correlation was found in patients with tuberculosis and premature birth (Rho= -0.395, p=0.034), weight decrease in newborns (Rho=-0.301, p=0.007) and a tendency to present a APGAR decrease at 1 minute, with poor recovery at 5 minutes (Rho= -0.233, p=0.04); the aforementioned results were obtained by using Spearman correlation (IC95%).The maternal mortality in pregnant women with tuberculosis was 11.5% (Fisher=0.032). Conclusion. Tuberculosis during pregnancy is related to adverse perinatal outcomes. In this study it was associated with preterm birth, intrauterine growth restriction, low APGAR and increases in maternal deaths.