Disseminated toxoplasmosis having hematologic involvement by bone marrow infiltration: a case report in a patient with HIV and brief review of coinfection
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Toxoplasma gondii is a common opportunist pathogen in patients with Acquired Immunodeficiency Syndrome (AIDS) Although its presentation is rare in geographic áreas with easy access to highly effective antiretroviral therapy (HAART). The usual clinical presentation involves the central nervous system, retina and respiratory tract. Toxoplasmosis with dissemination to bone marrow is uncommon in AIDS patients as evidenced in the few cases reported in the literature, most of them take place in patients after bone marrow transplant. Here it is described the case of a patient with a previous diagnosis of HIV infection and interruption of HAART who had fever and severe pancytopenia and who has documented pulmonary tuberculosis and toxoplasma tachyzoites presence in bone marrow aspirate. Toxoplasmosis disseminated to bone marrow should be considered as a differential diagnosis in patients with HIV,fever and hematologic involvement.
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