Prevalence of drug interactions in the Department of Internal Medicine at Hospital Universitario Hernando Moncaleano Perdomo-cross sectional study

Prevalencia de interacciones medicamentosas en el Departamento de Medicina Interna del Hospital Universitario Hernando Moncaleano Perdomo - estudio de corte transversal

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María Camila Erazo Díaz
Ana María Gómez Aroca
Andrea Liliana Gómez Arístizábal
Liseth Paola López Narváez
Margarita Polanía Durán
Andrea Catherine Salazar Trujillo
Adriana Gisely Salinas Jiménez
Juan Sebastián Bermeo
Giovanni Caviedes Pérez
Abstract

Objectives. To characterize drug interactions that took place at University Hospital Hernando Moncaleano Perdomo. Material and methods. Cross sectional descriptive study, with 130 patients admitted to Department of Internal Medicine located on the sixth floor of HUHMP Data analysis was carried outwith epi.Infov7.0. Results. It was found 702 theoretical interactions. There as a median of 3 interactions per patient. 73% of patients had a drug interaction,from which 93.3 were significant. Most frequent diagnosis were: HBP (HighBloodPressure) (12.3%), followed by neoplasm (11.5%), heartfailure (8.4%), type 2 diabetes mellitus (6.9%), CVE (cerebro-vascularevent) ischemic (3.8%), acute myocardial infarction (3.8%), heartdisease (3.1%), chronic kidney disease (3.8%),sepsis (7.7%), and tensión headache(6.2%). Conclusions. Pharmacodynamic interactions represent 71.8% of all data and the most frequent were those of synergism with potentiation (55.2%).

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Author Biographies / See

María Camila Erazo Díaz, Universidad Surcolombiana

Estudiante de Medicina

Ana María Gómez Aroca, Universidad Surcolombiana

Estudiante de Medicina

Andrea Liliana Gómez Arístizábal, Universidad Surcolombiana

Estudiante de Medicina

Liseth Paola López Narváez, Universidad Surcolombiana

Estudiante de Medicina

Margarita Polanía Durán, Universidad Surcolombiana

Estudiante de Medicina

Andrea Catherine Salazar Trujillo, Universidad Surcolombiana

Estudiante de Medicina

Adriana Gisely Salinas Jiménez, Universidad Surcolombiana

Estudiante de Medicina

Juan Sebastián Bermeo, Universidad Surcolombiana

Estudiante de Medicina

Giovanni Caviedes Pérez, Universidad Surcolombiana.

Médico especialista en Medicina Interna y Epidemiología, Universidad Surcolombiana. Especialista en Farmacología Clínica, Universidad de la Sabana. Docente Universidad Surcolombiana.
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